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Results Respondents in both groups were primarily white, female, and in their mid-forties nontraditional users to upper forties traditional users. Anticonvulsant and proconvulsant effects of tramadol, its enantiomers and its M1 metabolite in the rat kindling model of epilepsy. Other than demographics, the survey covered a broad variety of topics related specifically to tramadol, including the following: The tramadol was received within 24 hours, and numerous phone calls and emails were received almost immediately to refill the prescription some offers included up to pills in a single order and have continued on a monthly basis for over three years thus far. The most logical explanation for these findings is that the lack of physician oversight of dosage schedules, contraindicated conditions, and concomitant medications, were responsible for the increased intensity and frequency of adverse events in the nontraditional users. There are several possible interpretations of the latter motivation.

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Results Demographics As shown in Table 1 , both traditional and nontraditional users were primarily white and female. While the recent focus, appropriately, has been placed on the regulation of online pharmacies, there is very little systematic research outside of case reports on two potentially more important basic issues: Results Respondents in both groups were primarily white, female, and in their mid-forties nontraditional users to upper forties traditional users. Quantifying income-related inequality in healthcare delivery in the United States. They also provided a more complete medical history [ 21 ].