Understanding Hyperoxaluria

By | September 22, 2019

When a person with PH1 has a kidney stone, symptoms can include: • Flank pain • Urinary tract infections • Painful urination • Blood in the urine

People with PH1 often experience the formation of oxalate stones throughout the urinary tract and kidneys. Most often, kidney stones are the first sign of hyperoxaluria. Kidney stones are uncommon in childhood. For this reason, all young people with kidney stones should have a complete evaluation by a doctor.

Symptoms of a kidney stone may include:

  • Severe or sudden abdominal pain or pain in the side
  • Blood in the urine
  • Urinary tract infection
  • Frequent urge to urinate
  • Pain when urinating
  • Fever and chills

Some individuals are not diagnosed until after their kidneys have failed, and they require dialysis to help filter waste products from the blood.

Untreated primary hyperoxaluria can eventually damage a person’s kidneys and they may stop working. For some people, this is the first sign of the disease.

Symptoms of kidney failure may include:

  • Decrease in urine amount or not being able to urinate at all
  • Feeling generally ill or tired, or having heavy fatigue
  • Loss of appetite, nausea, and vomiting
  • Pale skin color related to anemia

Oxalosis in its late stages can cause a variety of complications in addition to those with the kidneys. This can include bone disease, anemia, skin ulcers, heart and eye problems, and, in children, a failure to develop and grow normally.

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