Tag Archives: targets

Dynamic model of SARS-CoV-2 spike protein reveals potential new vaccine targets

A new, detailed model of the surface of the SARS-CoV-2 spike protein reveals previously unknown vulnerabilities that could inform development of vaccines. Mateusz Sikora of the Max Planck Institute of Biophysics in Frankfurt, Germany, and colleagues present these findings in the open-access journal PLOS Computational Biology. SARS-CoV-2 is the virus responsible for the COVID-19 pandemic.… Read More »

Novel drug targets tumor growth in advanced kidney cancer

Scientists report promising activity of a novel drug that targets a key molecular driver of clear cell renal cell carcinoma in patients with metastatic disease. Researchers from Dana-Farber Cancer Institute report a response rate of 24 percent across all risk categories of patients given an oral first-in-class agent that targets hypoxia inducible factor (HIF) 2-a, which promotes… Read More »